ACE-167 is a novel synthetic peptide reference compound engineered for advanced research in endocrine regulation, hypogonadism models, and muscle wasting (cachexia) pathways. Operating as a selective peptide modulator of gonadotropic and anabolic signaling, ACE-167 enables laboratories to evaluate endogenous testosterone axis modulation and myocyte protein retention under catabolic stress.
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ACE-167 is an investigational, synthetic peptide reference compound developed for preclinical evaluation across endocrinology, metabolic disease, and reproductive system models. Engineered as a stable peptide agent, ACE-167 targets key signaling pathways governing hypothalamic-pituitary-gonadal (HPG) axis balance, endogenous testosterone production, and skeletal muscle protein preservation during catabolic states.
Batch-verified for high analytical purity at Modern Aminos, ACE-167 is supplied in a pre-measured 2.5MG dry-fill oral capsule format (60 units per bottle). Researchers investigating endocrine recovery, anabolic-catabolic nitrogen balance, and metabolic disease pathways utilize ACE-167 alongside related endocrine and peptide reference standards available on the site, such as Enclomiphene and SLU-PP-332.
| Compound Name | ACE-167 |
|---|---|
| Quantity / Formats Offered | 2.5MG Dry-Fill Capsules (60 Units per Bottle) |
| Synonyms / Alt Names | ACE 167, Acesis Synthetic Peptide Reference |
| CAS Number | Private CAS# / Not Released |
| Chemical Class | Synthetic Endocrine-Modulating Peptide |
| Primary Target Areas | Endocrinology, Cachexia, Metabolic Disease, Hypogonadism Models |
| IUPAC Name | Synthetic Peptide Sequence (Acosis Reference) |
| InChIKey | Protected Synthetic Peptide Matrix |
| SMILES Code | Protected Synthetic Sequence |
The biochemical pathways and cellular targets:
When evaluating research efficacy and published scientific literature:
To evaluate endocrine receptor targeting, anabolic potency, and metabolic pathways, researchers compare ACE-167 against alternative reference standards available at Modern Aminos:
| Compound / Reference | Primary Class / Target | Core Mechanism of Action | Research Focus & Profile |
|---|---|---|---|
| ACE-167 | Synthetic Endocrine-Modulating Peptide | Modulates HPG axis gonadotropic signaling, suppresses catabolic ubiquitin-ligases, and supports lipid homeostasis | Focuses on hypogonadism models, cachexia protection, and multi-system metabolic regulation without direct androgen receptor agonism |
| Enclomiphene | Nonsteroidal Selective Estrogen Receptor Modulator (SERM) | Selectively blocks estrogen receptors at the pituitary to stimulate endogenous LH and FSH release | Focuses purely on nonsteroidal estrogen receptor antagonism and pituitary-testicular axis stimulation |
Yes, Modern Aminos is a highly trusted vendor for high-purity research chemicals and peptide reference standards. Every batch undergoes rigorous third-party analytical testing (including HPLC and Mass Spectrometry) to verify minimum 98%+ purity, correct sequence identity, and complete absence of heavy metals or synthetic impurities.
ACE-167 is researched primarily as an endocrine and metabolic modulator. Laboratory studies evaluate its role in treating hypogonadism models, mitigating cachectic muscle wasting, and regulating glucose and lipid parameters in non-alcoholic fatty liver models.
Via central endocrine receptors to promote endogenous gonadotropin release. In testicular cell culture assays, this signaling cascade supports Leydig cell enzymatic activity, stimulating endogenous testosterone biosynthesis.
In muscle cell lines, it suppresses ubiquitin-ligase enzymes responsible for protein degradation while stimulating Akt phosphorylation. This dual action helps maintain muscle fiber size and protein density under catabolic stress.
Modern Aminos is provided in pre-measured 2.5MG dry-fill solid capsules (60 units per bottle). This format ensures exact unit-mass accuracy for solid-state laboratory assays, preventing weighing errors and eliminating reconstitution handling variance.
Exogenous testosterone directly activates androgen receptors and triggers severe negative feedback, suppressing natural LH/FSH production. It acts as a peptide modulator that supports natural endocrine signaling and tissue preservation without suppressing central pituitary function.
Enclomiphene is a nonsteroidal SERM that works exclusively by blocking pituitary estrogen receptors to increase LH and FSH. ACE-167 is a synthetic peptide that combines endocrine axis stimulation with direct anti-cachectic and metabolic protective signaling.
Bottles containing dry-fill capsules should be stored tightly sealed in a cool, dry environment (15°C to 25°C) away from direct sunlight, excess heat, and humidity. Stored under controlled room conditions, capsules maintain full chemical stability throughout their designated shelf life.
Disclaimer: All compounds and research materials provided by Modern Aminos are strictly for laboratory and research professional use only. They are not approved for human or animal use nor consumption by the Food and Drug Administration (FDA). These products should not be used for any form of in vivo experimentation or for any other non-laboratory purpose. Any violation or indication of human or animal use will result in immediate removal from being able to purchase products in the future. By purchasing these products, you acknowledge that they will be used exclusively within a controlled and qualified research environment.
The products offered by Modern Aminos are intended strictly for laboratory research purposes only and are sold exclusively to qualified professionals, institutions, and entities. These products are not for human consumption, veterinary use, or any other application involving living organisms, including but not limited to diagnostic, therapeutic, or recreational purposes.
By purchasing this product, you confirm that:
Modern Aminos does not claim that this product is approved by the U.S. Food and Drug Administration (FDA) for any purpose. The statements regarding this product have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
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If you have questions about the safe and lawful use of this product, consult a qualified professional with expertise in laboratory research. By proceeding with this purchase, you agree to these terms and conditions.